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The causes and factors of changes in the structure of the uterine cavity The middle layer of the uterus is heterogeneous – it is not a disease but rather a pathologic process of changing the homogeneity of the structure of the uterus in a number of different diseases, such as endometriosis (benign tumor growth)Answer 'Heterogenous uterus' is a description used to describe the appearance of the uterus after an ultrasound exam is done All that this means is that the ultrasound appearance of the uterus is not totally uniform The two most common causes of heterogenous uterus are uterine fibroids, which are benign muscular growths in the uterine wallEnlarged, globular uterus with diffusely heterogeneous echotexture of the myometrium and small myometrial cysts Characteristic saccular contrast material collections (arrowheads) protruding beyond the normal contour of the endometrial cavity Enlarged uterus with posterior thickening of the myometrium and multiple small cystic areas (arro...